TABLE 2.

Kinetic and mechanical properties of receptor-ligand tether bonds

Receptor	Ligand	(s−1)	σ (Å)	Reference
GPIbα (WT)	vWF-A1(WT)	5.66	0.058	This work
GPIbα (Q232V)	vWF-A1(WT)	7.15	0.06	This work
GPIbα (K237V)	vWF-A1(WT)	2.56	0.089	This work
GPIbα (WT)	vWF-A1(WT)	0.0038	—	Miura et al. (2000)
GPIbα (WT)	vWFA1(type2B)	0.0036	—	Miura et al. (2000)
GPIbα (WT)	vWF-A1(WT)	3.21	0.18	Doggett et al. (2002)
GPIbα (WT)	vWF-A1(type2B)	0.56	0.26	Doggett et al. (2002)
GPIbα (G233V)	vWF-A1(WT)	0.55	0.29	Doggett et al. (2003)
L-selectin	PNAd	6.80	0.2	Alon et al. (1997)
P-selectin	PSGL-1	1.1	0.29	Ramachandran et al. (1999)
α4β7/Ca	MAdCAM-1	0.046	0.91	Chateau et al. (2001)