Figure 5.

Expression of the doublecortin-positive (DCX+) cells in the hippocampal dentate gyrus after 1 week of antibody washout. Mice exposed to anti-NMDAR antibodies did not show changes in the expression of DCX+ cells in the hippocampal granule zone (GZ) upon removal of anti-NMDAR antibodies or control antibodies for 1 week (A). Longitudinal changes in the expression of DCX+ cells in the hippocampal GZ were similar in both groups at all assessed bregma levels (B). The data represent mean ± SEM; n = 7–8 mice per group. Representative microscopic images showing the DCX immunoreactivity in the hippocampal GZ of mice treated with antibodies (C and insert). Scale bar: 50 μm (insert: 15 μm).