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. Author manuscript; available in PMC: 2026 Apr 1.
Published in final edited form as: Exp Neurol. 2024 May 25;378:114838. doi: 10.1016/j.expneurol.2024.114838

Table 1.

Summary of the memory test outcomes during the antibody washout in mice treated with anti-NMDAR and control antibodies.

Assessments (weeks from IgG removal), units Anti-NMDAR IgG Control IgG p-value
Memory test indexes, mean ± SEM
Object location (1), % 43.2 ± 5.0 60.1 ± 3.9 p = 0.02
Y maze (1), % 67 ± 3.7 66.4 ± 3.4 p = 0.9
Object location (3), % 43.2. ± 5.7 63.1 ± 3.9 p = 0.009
Barnes maze, failure rate: trials 3 and 4 (4), % 0 and 30 100 and 70 p = 0.03
Barnes maze, primary latency (4), sec 55.1 ± 21.4 82.7 ± 18.7 p = 0.35
Barnes maze, total time in the target quadrant (4), sec 86.2 ± 9.8 73.3 ± 8.0 p = 0.32
Barnes maze, time in the target quadrant after discovery of the hole (4), sec 69.3 ± 14.6 43.6 ± 8.5 p = 0.13
Y maze (4), % 55.0 ± 3.1 71.0 ± 2.3 p = 0.0006