Effects of Zn2+ on the dimer single channel conductance. Unitary events measured at −160 mV in an outside-out patch in oocytes injected with the (KDC1-KAT1) dimer, before control (upper trace), and after the application of Zn2+ (lower trace) to the bath solution. The data were filtered at 0.5 kHz and sampled at 10 kHz. Internal solution was 100 mM KCl, 2 mM MgCl2, 11 mM EGTA, 10 mM HEPES, and 0.5 mM ATP, at pH 7.2. External standard ionic solution, pH 5.6.