TABLE 5.

Relative change in activity at lytic concentrations ([CI_t] ≈ 0 and [Cro_t] ≈ 200 nM) corresponding to perturbations as performed in Table 3

	+1 kcal/mol		−1 kcal/mol
	PRM	PR	PRM	PR
ΔG1′	0	0.6	0	−0.6
ΔG2′	0	0.6	0	−0.6
ΔG3′	2.3	0	−0.8	0
ΔG12′	−0.3	0	1.1	−0.2
ΔG23′	0.1	0.1	−0.2	−0.2
ΔG123′	0.3	0.3	−0.6	−0.6
ΔGRM	−0.8	0	2.6	0
ΔGR	0	−0.7	0	0.8

Wild-type activity in regime 3 is 1.0 × 10⁻⁴ s⁻¹ at P_RM and 6.1 × 10⁻³ s⁻¹ at P_R.