TABLE 1.
Strain | Mean colon wt (mg)a at day:
|
||||||
---|---|---|---|---|---|---|---|
0 | 6 | 10b | 14b | 18b | 21b | 24b | |
Wild type | 102 ± 6 | 123 ± 11 | 188 ± 20 | 193 ± 16 | 190 ± 17 | 173 ± 19 | 168 ± 11 |
iNOS (−/−) | 100 ± 4 | 120 ± 14 | 206 ± 26 | 208 ± 24 | 243 ± 28 | 203 ± 16 | 174 ± 9 |
C. rodentium infection results in increased colon weights in both wild-type and iNOS-deficient mice. Values represent the mean colon weight ± 1 SEM from three independent experiments, each with groups of four to five mice.
Significantly increased colon weight in both the wild-type and iNOS-deficient strains compared to that of uninfected mice of the same strain (P < 0.05).