Table 3.
Association between log(ACE2) serum level and demographics and clinical characteristics of MS patients and healthy controls.
| Characteristic | MS patients | Healthy controls | ||
|---|---|---|---|---|
| Median [IQR] | p-value | Median [IQR] | p-value | |
| Gender | 0.04 | < 0.001 | ||
| Male | 1583.28 [1359.64–2085.16] | 1758.25 [1088.67–2816.53] | ||
| Female | 2035.08 [1609.00–2394.38] | 954.64 [799.62–1249.26] | ||
| Comorbidity | 0.419 | – | – | |
| No | 1864.26 [1472.24–2341.72] | |||
| Yes | 2038.74 [1609.18–2507.99] | |||
| MS type | 0.403 | – | – | |
| CIS | 2157.70 [1504.51–2423.44] | |||
| RR-MS | 1850.60 [1516.92-2276.30] | |||
| PR-MS | 2174.96 [1599.59-3714.02] | |||
| EDSS level | 0.614 | – | – | |
| Normal-mild disability | 1902.02 [1557.78-2386.56] | |||
| Moderate-severe | 1850.60 [1452.69-2231.53] | |||
| Previous relapse in the last 24 months | 0.963 | – | – | |
| No | 1859.14 [1569.71-2369.28] | |||
| Yes | 1947.32 [1427.37-2354.73] | |||
| Currently on DMT | 0.057 | – | – | |
| No | 2092.36 [1657.46-2575.18] | |||
| Yes | 1799.80 [1459.03-2239.02] | |||
Significant values are in bold.