Table 6.

Relationship between ACE2 polymorphisms and demographics and clinical characteristics of MS patients.

Characteristic	rs2074192		rs2285666
	Test	p-value	Test	p-value
Age, yearsa	2.254	0.324	0.149	0.928
Gender	114.107	< 0.001 b	51.907	< 0.001 c
BMIa	1.284	0.526	4.156	0.125
Comorbidity	5.251	0.074c	0.337	0.843c
Age at MS onset, yearsa	2.033	0.362	0.278	0.870
Age at diagnosisa	2.246	0.325	0.531	0.767
MS disease duration, monthsa	0.561	0.755	0.196	0.907
MS type	5.283	0.260c	2.355	0.666b
EDSS scorea	1.106	0.575	5.334	0.069
EDSS level	6.645	0.036 c	4.883	0.084c
Previous treatment	0.503	0.781c	1.359	0.516c
Previous relapse in the last 24 months	2.529	0.289c	0.729	0.696c
Number of relapses in the last 24 monthsa	1.214	0.545c	0.970	0.616c
Currently on DMT	4.063	0.132c	7.566	0.022 c
rs2285666	102.65	< 0.001 b	–	–

^aKruskal-Wallis Test.

^bFisher’s Exact Test.

^cChi-square test.

Significant values are in bold.