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. 2004 Mar;86(3):1332–1344. doi: 10.1016/S0006-3495(04)74205-8

FIGURE 10.

FIGURE 10

Substeps of a-subunit rotation. (Left) When both cAsp-61 residues are deprotonated, the average internal potential acting on the a-subunit is symmetric (dashed line). The F1 load (dotted line) shifts the minimum of the average potential to the right (solid line). This figure corresponds to steps a and f in Fig. 6. (Right) When cAsp-61 on c2R receives a proton from the periplasm, the average internal potential becomes asymmetric. The minimum of the total potential is shifted to the left in this case. This figure corresponds to steps c and d in Fig. 6.