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. 2026 Mar 29;16:10693. doi: 10.1038/s41598-026-46172-y

Table 2.

Association between ICH onset time and admission NIHSS score.

06:00–10:00 10:00–14:00 14:00–18:00 18:00–22:00 22:00–02:00 02:00–06:00
Admission NIHSS score (Mean ± SD) 8.5 ± 8.8 8.0 ± 8.8 8.4 ± 8.9 9.4 ± 9.4 9.2 ± 9.1 9.2 ± 9.0
Unadjusted r (95% CI) Reference − 0.4 (− 0.6, − 0.2) − 1.3 (− 1.6, − 1.1) − 1.2 (− 1.5, − 0.8) − 1.2 (− 1.5, − 0.8) − 0.4 (− 0.7, − 0.2)
Unadjusted P value Reference  < 0.01  < 0.01  < 0.01  < 0.01  < 0.01
Adjusted r (95% CI) Reference − 0.2 (− 0.5, 0.1) − 0.5 (− 0.8, − 0.1) − 0.5 (− 0.9, − 0.0) − 0.2 (− 0.6, 0.2) − 0.0 (− 0.3, 0.3)
Adjusted P value Reference 0.28 0.01 0.03 0.40 0.97

Adjusted variables: age, gender, body mass index, systolic blood pressure, diastolic blood pressure, history of subarachnoid hemorrhage, hypertension, diabetes, atrial fibrillation, chronic obstructive pulmonary disease, and fasting blood glucose, homocysteine, creatinine, season and time from onset to arrival.