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. 2002 Nov;70(11):6021–6031. doi: 10.1128/IAI.70.11.6021-6031.2002

TABLE 2.

Complement-mediated bactericidal titers of pooled mouse and guinea pig antisera against homologous and heterologous strainsa

Homologous strain Bactericidal activity (1/titerb)
Heterologous strain Bactericidal activity (1/titerb)
Mouse
Guinea pig
Mouse
Guinea pig
Sequential Mix Sequential Mix Sequential Mix Sequential Mix
1000 128 6 64 16 BZ147 40 51 9 >128
8047 300 125 >128 >128 CU385 128 <4 12 4
BZ198 220 1000 40 16 H44/76 >128 21 64 8
BZ83 109 205 24 >128 MC58 8 <4 >128 <4
M986 101 133 128 >256 NG3/88 4 <4 9 5
NGP165 120 90 64 >256 NGH15 >128 <4 >128 92
NMB 441 141 >256 >256 NGH38 <4 <4 >128 <4
RM1090 >128 >128 >1024 >1024 S3032 400 230 32 <4
Z1092 >128 >128 >1024 >1024 S3446 <4 <4 24 4
SWZ107 40 <4 <4 <4
a

For definitions of homologous and heterologous strains, see Table 1 and the text.

b

That is the dilution of serum that results in 50% killing of bacteria after 60 min of incubation in the presence of human complement.