TABLE 1.
4 fast | 1 slow:3 fast | 2 slow:2 fast | 3 slow:1 fast | 4 slow |
---|---|---|---|---|
1.6 | 4.7 | 12.3 | 28.1 | 80.1 |
2.3 | 4.5 | 13.1 | 22.8 | 61.8 |
2.1 | 3.8 | 12.1 | 32.1 | 77.2 |
1.8 | 4.3 | 11.5 | 23.5 | 84.3 |
2.2 | 4.9 | 12.9 | 29.1 | 102.0 |
2.4 | 4.3 | 13.8 | 26.0 | |
4.8 | 13.4 | 45.2 | ||
5.0 | 11.8 | 25.5 | ||
4.5 | 10.9 | 26.1 | ||
3.9 | 11.9 | 33.0 | ||
4.9 | 11.9 | 35.8 | ||
3.7 | 13.0 | 41.1 | ||
3.3 | 12.1 | 37.2 | ||
5.1 | 13.9 | 31.2 | ||
4.8 | 12.2 | 31.0 | ||
5.6 | 14.1 | 26.2 | ||
4.8 | 11.4 | 23.1 | ||
5.7 | 10.9 | 21.3 | ||
4.9 | 11.3 | 22.5 | ||
5.9 | 12.7 | 24.7 | ||
6.2 | 9.1 | 20.4 | ||
5.2 | 10.5 | 21.6 | ||
4.0 | 14.3 | 30.1 | ||
4.8 | 13.3 | 28.2 | ||
5.6 | 12.6 | |||
5.3 | 12.3 | |||
10.8 | ||||
15.3 | ||||
2.0 ± 0.12 | 4.8 ± 0.3 | 12.4 | 28.5 ± 1.81 | 80.8 ± 6.4 |
11.6 | ||||
11.8 | ||||
9.9 | ||||
13.0 | ||||
12.6 | ||||
10.0 | ||||
12.2 ± 0.67 |
All values are in milliseconds. “Fast” designates the Kir6.2ΔC26/T171 wild-type subunit. “Slow” designates the Kir6.2ΔC26/171A mutant subunit. At the bottom of each column of values is the mean of means ± SE. Each mean of means is significantly different from each of the other mean of means, P < 0.001.