TABLE 1.

The mean conductance fitted by Gaussian distribution (Λ_c), the occurrence (channels/min), the fitted lifetimes (see text) of the single-channel events (s), the significant F-test (P) of the lifetimes, and the total number (N_t) of AβP (1–40) channels in different PLMs at different applied potentials

PLM	V (mV)	Λc (nS) ± SD	Occurrence ± SD	τ1(s)	τ2(s)	P	Nt
DOPS:DOPE	60	0.700 ± 0.30	5.62 ± 0.14	1.29	–	–	1650
POPC:Ch	80	0.013 ± 0.01	0.50 ± 0.04	0.99	–	–	129
	100	0.018 ± 0.01	1.22 ± 0.12	0.20	2.60	–	108
	120	0.016 ± 0.01	2.97 ± 0.30	2.45	–	0.13	107
POPC:Erg	120	0.015 ± 0.00	3.13 ± 0.12	3.80	–	0.65	631
7-DHC	40	0.062 ± 0.04	7.91 ± 0.41	4.01	–	–	372
	20	0.081 ± 0.04	3.68 ± 0.11	4.54	–	0.79	1164
	−20	0.090 ± 0.03	4.42 ± 0.15	4.35	–	0.65	508
	−40	0.040 ± 0.03	2.40 ± 0.18	2.81	–	0.58	176
OxCh	120	0.072 ± 0.03	4.23 ± 0.15	1.44	8.90	–	748
	100	0.095 ± 0.04	3.23 ± 0.20	1.98	–	0.23	272
	80	0.100 ± 0.06	1.82 ± 0.08	2.57	–	–	464
	60	0.120 ± 0.06	1.51 ± 0.05	0.16	3.33	–	724
	40	0.160 ± 0.10	2.32 ± 0.09	0.40	5.26	–	611
	20	0.540 ± 0.42	2.97 ± 0.06	0.40	3.02	–	2080
	−20	0.980 ± 0.43	4.68 ± 0.17	1.71	–	–	791
	−40	0.180 ± 0.10	3.33 ± 0.12	4.00	–	0.34	751
	−60	0.170 ± 0.08	3.10 ± 0.09	3.70	–	0.12	1071
	−80	0.110 ± 0.06	3.82 ± 0.22	1.65	12.38	–	284
	−100	0.102 ± 0.07	2.99 ± 0.25	2.14	–	0.14	140
	−120	0.063 ± 0.05	7.94 ± 0.44	2.25	–	0.12	329