FIGURE 10.

Probabilities of different states (p_i), open probabilities (P_o), and the average fractional conductance (P_c) computed with a five-state MscL model. The parameters for individual states used in the model are given in Table 1. The effective open probability P_o^eff weighted by substate conductances was calculated from the integral conductance presented as G/g_O . The fitting of the weighted (P_o^eff) and nonweighted (P_o) open probabilities (inset) gave slopes and energies almost identical to the parameters of the fully open state included in the model. See Discussion.