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The logarithm of k1, the rate constant of the M-decay, is plotted against pH in the medium. The mutants are R72A (▪), R72K (♦), R72Q (▴), R72S (▾), R72A/D193N (□), and R72A/D193E (
), and data of the wild-type are shown by ○. Experimental conditions were the same as in Fig. 3.
