FIG. 3.

Sequence alignment of L. pneumophila PlaA with members of the GDSL family. Sequences of the 12 closest matches to PlaA are aligned along the five conserved blocks of the GDSL family. An asterisk designates those positions where an amino acid is conserved in at least six of the homologs. The amino acids comprising the putative catalytic triad of PlaA are shown in italics, and the residues conserved in the SGNH family are underlined. The digits before and after blocks I to V indicate the number of amino acid residues present before and after the conserved regions.