Table 2:
LMM showing the direct association between the use of RAASIs and serum potassium.
| Longitudinal univariate random intercept analysis | Longitudinal multivariate analysis | |||||
|---|---|---|---|---|---|---|
| β | 95% CI | P-value | Adjusted β | 95% CI | P-value | |
| RAASIs (yes) | 0.05 | 0.03–0.07 | <.001 | 0.100 | 0.05–0.15 | <.001 |
| Age (years) | 0.003 | 0.001–0.005 | .001 | |||
| Male | −0.011 | −0.06–0.04 | .646 | |||
| Albumin (g/dl) | 0.188 | 0.15–0.23 | <.001 | |||
| Hypertension (yes) | 0.004 | −0.05–0.06 | .124 | |||
| Use of calcium channel antagonists (yes) | 0.03 | −0.008–0.07 | .122 | |||
| COPD (yes) | −0.081 | −0.154 to −0.008 | .03 | |||
| CRP (g/dl) | −0.002 | −0.0033 to −0.0006 | .014 | |||
| Diabetes (yes) | −0.087 | −0.14 to −0.03 | .001 | |||
| Diuresis (yes) | −0.116 | −0.17 to −0.06 | <.001 | |||
| Serum iron (ng/ml) | −0.019 | −0.05–0.01 | .199 | |||
| Heart failure (yes) | −0.061 | −0.14–0.02 | .151 | |||
| Serum phosphate (mg/dl) | 0.077 | 0.06–0.09 | <.001 | |||
| TSAT (%) | 0.001 | 0.0003–0.0024 | .011 | |||
| Visit | 0.011 | 0.008–0.015 | <.001 | |||
| Kt/V | 0.034 | −0.018–0.087 | .201 | |||
β refers to the slope of the univariate LMM, whereas adjusted β refers to the slope of the multivariate LMM.