TABLE 1.
Incidence of bistability (BS) and limit cycles (LC) among 100,000 random searches, for Cases 1–4 (positive feedback only)
| Hypothetical cases | BS | LC |
|---|---|---|
| Case 1: CDC25_1p | 32 | 11 |
| Case 1: CDC25_2p | 796 | 40 |
| Case 1: CDC25_5p | 2090 | 1467 |
| Case 2: wee1_1p | 1 | 0 |
| Case 2: wee1_2p | 90 | 12 |
| Case 2: wee1_5p | 3223 | 476 |
| Case 3: CAK_1p | 0 | 0 |
| Case 3: CAK_2p | 20 | 0 |
| Case 3: CAK_5p | 437 | 0 |
| Case 4: CDC25_1p + wee1_1p | 224 | 25 |
| Case 4: CDC25_1p + wee1_1p + CAK_1p | 729 | 40 |
| Case 4: CDC25_2p + wee1_2p + CAK_1p | 3639 | 125 |
| Case 4: CDC25_2p + wee1_2p + CAK_2p | 4131 | 134 |
| Case 4: CDC25_5p + wee1_5p + CAK_1p | 1313 | 750 |