TABLE 3.

Incidence of bistability (BS) and limit cycles (LC) among 100,000 random searches, using simplified models A–C simulating multisite phosphorylation

	Model A		Model B		Model C
Hypothetical cases	BS	LC	BS	LC	BS	LC
Case 1: CDC25_1p	0	0	0	0	0	0
Case 1: CDC25_2p	27	3	7	2	82	3
Case 2: wee1_1p	0	0	0	0	0	0
Case 2: wee1_2p	6	0	5	0	6	0
Case 3: CAK_1p	0	0	-	-	-	-
Case 3: CAK_2p	14	0	-	-	-	-
Case 4: CDC25_1p + wee1_1p	0	0	0	0	0	0
Case 4: CDC25_2p + wee1_2p + CAK_1p	577	35	121	0	437	20
Case 5d: positive + negative feedback	33	611	2	0	9	595
Case 5b: positive + negative feedback	40	557	36	100	53	2275