TABLE 1.

Tryptophan backbone conformation in cyclic peptides, 5°C, and predicted χ₁ rotamer populations from backbone-dependent rotamer library

			Predicted population
Peptide	Sequence	φ, ψ	χ1 = −60°	χ1 = 180°	χ1 = 60°
2a	c[d-PWTFFpY]	−70°, −32°	0.62	0.22	0.16
2b	c[d-PWTpYFF]	−70°, −29°	0.62	0.22	0.16
3	c[d-PpYWTFF]	−100°, 164°	0.85	0.08	0.07
4a	c[d-PpYTWFF]	−67°, 5°	0.52	0.01	0.47
4b	c[d-PpYFWFT]	−48°, −48°	0.25	0.71	0.04
5*	c[d-PpYTFWF]	−104°, −46°	0.68	0.32	0
6	c[d-PpYTFFW]	−155°, 139°	0.01	0.75	0.24

^*25°C, Adams et al., 2002.