|
D = 400 μm2/s |
Diffusion coefficient of calcium ions |
|
Ninit = {100, 300} |
Number of calcium ions in spine at time 0 |
|
NAM = {50, 60} |
Number of type 1 proteins in spine |
|
Ncal = {10, 30} |
Number of type 2 proteins |
|
Npumps = {0, 4, 10} |
Number of pumps |
|
Nchannel = 5 |
Number of channels |
|
N(t) = |
Number of calcium ions in spine at time t
|
|
δ1 = 0.01 μm |
Radius of a calcium binding site on a type 1 protein |
|
δ2 = 0.02 μm |
Radius of a calcium binding site on a type 2 protein |
 = 50 μm−1/s |
Forward binding rate of calcium to type 1 proteins |
 = 50 μm−1/s |
Forward binding rate of calcium to type 2 proteins |
 = 500s−1
|
Rate of calcium dissociation from type 1 proteins |
 = 25s−1
|
Rate of calcium dissociation from type 2 proteins |
|
R = 0.5 μm |
Radius of the head |
|
d = {.2, 0.4} |
Diameter of the neck |
|
l = {.3, .6, 1} |
Length of the neck |
|
Spumps = 0.01 μm |
Size of the active center of the pumps |
|
τpumps = 9 ms |
Characteristic time of pumps |
