Table 2. . Summarized patient baseline characteristics of the the Xiangya retrospective cohort and the multicenter cohort used for model extrapolation.
| Patient cohort | Xiangya patient cohort (n = 512) |
Multicenter patient cohort (n = 300) |
p-value |
|---|---|---|---|
| Mean ± SD/% | Mean ± SD/% | ||
| Age (years) | 39.8 ± 13.7 | 42.8 ± 12.9 | 0.002 |
| Male proportion | 68.6% | 63.0% | 0.106 |
| Residence location | |||
| Provincial capital city | 22.9% | 21.3% | 0.616 |
| Regional city | 15.2% | 62.7% | <0.001 |
| County | 37.7% | 11.7% | <0.001 |
| Rural area | 23.0% | 4.3% | <0.001 |
| Unknown | 1.2% | 0.0% | 0.145 |
| Disease severity | |||
| Moderate | 24.2% | 58.7% | <0.001 |
| Severe | 75.8% | 41.3% | <0.001 |
| Skin lesion location | |||
| Lower limbs | 75.4% | 85.3% | <0.001 |
| Upper limbs | 73.8% | 68.3% | 0.811 |
| Trunk | 73.4% | 72.7% | 0.093 |
| Head | 68.0% | 69.0% | 0.760 |
| Health utility | 0.850 ± 0.065 | 0.653 ± 0.281 | <0.001 |
Bold value indicate statistical significance.
Values of p are provided to quantify differences in baseline characteristics between cohorts and to inform the interpretation of model extrapolation; they are not intended for hypothesis-driven between-group inference.
PASI: Psoriasis Area and Severity Index; SD: Standard deviation.