TABLE 1.

Backbone RMSD between time-averaged enzyme structures in different solvents

	Crystal	WAT	OCT	THF	ACN
Crystal	0	0.62	0.96	0.59	0.67
WAT	0.62	0	0.95	0.56	0.56
OCT	0.96	0.95	0	0.78	0.94
THF	0.59	0.56	0.78	0	0.54
ACN	0.67	0.56	0.94	0.54	0

RMSD values between these structures and the crystal structure in water are also included. RMSD values are in Å units.