FIGURE 8.
Semilogarithmic concentration (ps) versus time plots for data generated from one-compartment model with first-order input and elimination based on Eq. 7. The parameter values (in arbitrary units) used for the generation of data are: Vm = 0.4, Km0 = 0.2, h = 1.0, dose X0 = 100, and either a high 1.0 (A) or low 0.01 (B) value for the absorption rate constant. The lines represent the fitting results of the two models: classic MM (A and B insets) and fractal model (A and B) to data.