Extrasystolic restitution/post-extrasystolic potentiation protocol; see text for details. (A) Model Ca2+ transients (ordinate, nM) versus time (abscissa, ms). Thick trace represents beats at priming basic cycle length of 1500 ms. (B) Experiment in ferret ventricle with fluorescence (ordinate, arbitrary units) versus time (abscissa, ms, adapted from Wier and Yue, 1986). L, uncalibrated luminescence signal.