TABLE 1.

A set of parameter values that give a good fit between mean-field theory and the SB data for the six mutant strains

m	0	1	2	3	4
E0(1, m)	0.864	0.310	−0.147	−8.02	−20.1
E0(2, m)	4.69	–	−1.04	–	−7.97
E1(1, m)	30	2.10	1.41	0.763	0.740
E1(2, m)	30	–	30	–	30
(1, m)	2.43	21.3	18.0	0.0314	6.49 × 10−7
(1, m)	3.7 × 109	128.9	85.4	204.2	727.1
(2, m)	0.257	–	32539	–	24.9
(2, m)	2.5 × 1010	–	9.8 × 1017	–	7.7 × 1017
EJ(q,q′)		q′ = 1		q′ = 2
q = 1		0		−4.40
q = 2		−6.41		−1.38

The local parameters for each receptor type, E₀, E₁ (in unit of thermal energy) and (in unit of μM), are listed for each relevant receptor type characterized by (q, m), where q = 1 for Tar and q = 2 for Tsr, and m is the receptor methylation level. Values of (q, m) = exp(E₁ − E₀) are also included for reference; the effective dissociation constant is a complicated combination of and and it also depends on the actual activity. The coupling constants E_J(q, q′) (listed in the lower table) depend on the receptor species labels q and q′ for two neighboring receptors.