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. 2004 Sep;87(3):1672–1685. doi: 10.1529/biophysj.104.043174

FIGURE 4.

FIGURE 4

Effects of PEGs added from the extracellular side or both sides of the patch on single maxi-anion channel currents. (A) Representative single-channel events recorded when PEG 200 was added only to the pipette solution (left panel) and to both the pipette and bath solutions (middle panel), and when PEG 4000 was added to both the pipette and bath solutions (right panel). (B) Current-voltage relationships for the maxi-anion channel with PEG 200 present only in the pipette (left panel) and in both the pipette and bath (middle panel), and PEG 4000 present in both the pipette and the bath solution (right panel). Each symbol represents the mean of 5–19 observations obtained from at least five different patches. Solid lines are linear fits with slopes corresponding to the unitary inward conductances of 327.0 ± 9.7 pS, 227.5 ± 4.9 pS, and 404.5 ± 3.2 pS, and the outward conductances of 257.7 ± 5.8 pS, 216.8 ± 7.1 pS, and 395 ± 11 pS in the left, middle, and right panels, respectively.