TABLE 5.
Reactions
| Abbreviation | Enzyme | Chemical reaction |
|---|---|---|
| Glycolysis and Rapoport-Leubering shunt | ||
| HK | Hexokinase | GLU + ATP → G6P + ADP + H |
| PGI | Phosphoglucoisomerase | G6P ↔ F6P |
| PFK | Phosphofructokinase | F6P + ATP → FDP + ADP + H |
| ALD | Aldolase | FDP ↔ GA3P + DHAP |
| TPI | Triose phosphate isomerase | DHAP ↔ GA3P |
| GAPDH | Glyceraldehyde phosphate dehydrogenase | GA3P + NAD + Pi ↔ 13DPG + NADH + H |
| PGK | Phosphoglycerate kinase | 13DPG + ADP ↔ 3PG + ATP |
| DPGM | Diphosphoglyceromutase | 13DPG + → 23DPG + H |
| DPGase | Diphosphoglycerate phosphatase | 23DPG + H2O → 3PG + Pi |
| PGM | Phosphoglyceromutase | 3PG ↔ 2PG |
| EN | Enolase | 2PG ↔ PEP + H2O |
| PK | Pyruvate kinase | PEP + ADP + H → PYR + ATP |
| LDH | Lactate dehydrogenase | PYR + NADH + H ↔ LAC + NAD |
| Pentose phosphate pathway | ||
| G6PDH | Glucose-6-phosphate dehydrogenase | G6P + NADP → 6PGL + NADPH + H |
| PGL | 6-phosphoglyconolactonase | 6PGL + H2O ↔ 6PGC + H |
| PDGH | 6-phosphoglycoconate dehydrogenase | 6PGC + NADP → RL5P + NADPH + CO2 |
| R5PI | Ribose-5-phosphate isomerase | RL5P ↔ R5P |
| Xu5PE | Xylulose-5-phosphate epimerase | RL5P ↔ X5P |
| TKI | Transketolase I | X5P + R5P ↔ S7P + GA3P |
| TA | Transaldolase | GA3P + S7P ↔ E4P + GA3P |
| TKII | Transketolase II | X5P + E4P ↔ F6P + GA3P |
| Adenosine nucleotide metabolism | ||
| PRPPsyn | Phosphoribosyl pyrophosphate synthetase | R5P + ATP → PRPP + AMP |
| PRM | Phosphoribomutase | R1P ↔ R5P |
| HGPRT | Hypoxanthine guanine phosphoryl transferase | PRPP + HX + H2O → IMP + 2Pi |
| AdPRT | Adenine phosphoribosyl transferase | PRPP + ADE + H2O → AMP + 2Pi |
| PNPase | Purine nucleoside phosphorylase | INO + Pi ↔ HX + R1P |
| IMPase | Inosine monophosphatase | IMP + H2O → ADO + Pi + H |
| AMPDA | Adenosine monophosphate deaminase | AMP + H2O → IMP + NH3 |
| AMPase | Adenosine monophosphate phosphohydrolase | AMP + H2O → ADO + NH3 |
| ADA | Adenosine deaminase | ADO + H2O → INO + NH3 |
| AK | Adenosine kinase | ADO + AMP → ADP + AMP |
| ApK | Adenylate kinase | 2ADP ↔ ATP + AMP |