TABLE 7.

Calculated changes in Boltzmann-averaged energy components, configurational entropy, and standard free energy, for binding of nabumetone with cyclodextrins (kcal/mol)

	α-CD	β-CD	γ-CD
	−18.88	−29.60	−27.90
	−2.83	−7.31	−7.10
	−2.23	−3.19	−3.61
	2.04	7.26	7.92
−TΔSconfig	19.06	24.35	23.32
	0.75	3.25	2.64
	−2.09	−5.24	−4.73
	−0.79	−0.05	0.82

See Table 3 for symbols.