TABLE 3.
Comparison of the L-type and RyR Ca2+ channels and mutant OmpF
Ca2+ channel type | Volume nm3 | g in CaCl2 pS | DNa/DCa in filter | PCa/PNa | [Ca2+] to reduce g by 50% |
---|---|---|---|---|---|
L-type* | 0.375 | 10 (saturated) | 20 | 100 | ≈1 μM |
RyR† | 0.380 | 150 (in 50 mM) | ≈10 | 5–7 | ≈5 mM |
(L)EAE | 2 | 158 (in 100 mM)‡ | 10 | 3–4¶ | >1 mM |
See Nonner and Eisenberg (1998) and references therein.
See Chen et al. (2003) and references therein.
Monomeric conductance, see Fig. 8A.
This study, under biionic conditions, 0.1 M NaCl // 0.1 M CaCl2, pH 7.4 (unpublished results).