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. 2004 Sep 3;87(5):3336–3343. doi: 10.1529/biophysj.104.040634

FIGURE 6.

FIGURE 6

Analysis of the elastic properties of BAECs under different cholesterol conditions. (A) Typical data of the dimensionless aspirated projection length, L/a, as a function of the negative applied pressure difference, P, for control, cholesterol-enriched, and cholesterol-depleted cells with their respective least-squares fit (solid lines). (B) Elastic modulus K for control (7 cells), enrichment (10 cells), and depletion (17 cells) as obtained by least-squares fit of a straight line to the data. Depleted cells are significantly stiffer (P < 0.05) than control and cholesterol-enriched cells. Mean ± SE. (C) Young's modulus E according to the homogeneous half-space model (Eq. 1) for the data shown in B. Depleted cells have a significantly larger Young's modulus (P < 0.05) than control and cholesterol-enriched cells. Mean ± SE.