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Effect of mtKATP channel modulators on the frequency of ΔΨm fluctuations
| Fluctuations per minute | |
|---|---|
| Control | 1.09 ± 0.04 |
| 5-Hydroxydecanoate (500 μM) | 1.09 ± 0.08 |
| Diazoxide 15 μM | 1.16 ± 0.14 |
| Diazoxide 300 μM | 0.97 ± 0.12 |
| ATP | 0.12 ± 0.02 |
| ATP + diazoxide 15 μM | 0.15 ± 0.03 |
| ATP + diazoxide 300 μM | 0.13 ± 0.01 |
Data are shown as mean ± SE, n = 3 experiments with 100 individual mitochondria were analyzed in each experiment.
