TABLE 2.
Putative 3D equivalent D-channel residues in different heme-copper oxidases
| A. ambivalens | T. thermophilus | P. denitrificans |
|---|---|---|
| Val-246 | Ile-235 | Glu-278* |
| Asp-167* | Phe-152 | Ser-189 |
| Glu-80* | Gln-82* | Ile-104 |
| Asn-113* | Ala-113 | Tyr-138 |
| Tyr-171* | Thr-156* | Ser-193* |
| Thr-170* | Ser-155* | Ser-192 |
| Phe-84 | Gln-86* | Gly-109 |
| Phe-109 | Ser-109* | Ser-134* |
| Val-22 | Phe-24 | Tyr-35* |
| Thr-19* | Thr-21* | Gly-32 |
| Asn-106* | Met-106 | Asn-131* |
| Tyr-89* | Tyr-91* | Tyr-114* |
| Ile-177 | Ile-162 | Asn-199* |
| Lys-93* | Arg-95 | Leu-118 |
| Lys-15* | Glu-17* | Asp-30 |
Polar residues likely to be involved in the proton translocation are marked with an asterisk.