FIGURE 6.
(A) Time-lapsed pictures demonstrating gelation/contraction for untreated extracts at t = 0 and t = 120 min. (B) Effect of actin depolymerizing and stabilizing drugs on contraction, here represented by the contracted gel area A normalized by initial gel area Ao. The disassembly of the actin network by latrunculin B prevents contraction, whereas addition of the stabilizing agent phalloidin accelerates the onset of contraction. (C) Effect of microtubule depolymerizing and stabilizing drugs on contraction. The disruption of the microtubule network by nocodazole accelerates whereas taxol stabilization inhibits contraction.