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. 2026 Mar 23;17:1707493. doi: 10.3389/fimmu.2026.1707493

Figure 1.

Schematic diagram showing clinical cohort study design, principal component analysis plot comparing healthy and SI-ALI groups, a Circos plot of bacterial genera distribution, boxplots comparing microbial diversity indices (Ace, Shannon, MDI) between groups, and a horizontal bar plot summarizing differential abundance of bacterial genera with statistical comparisons.

Intestinal Blautia participates in SI-ALI progression in humans. (A) Flowchart of patient recruitment, group allocation, and analytical procedures. (B) Partial Least Squares Discriminant Analysis (PLS-DA) scatter plot of fecal samples from healthy controls and SI-ALI patients (phylum level). (C) Circos plot delineating taxon-sample relationships in SI-ALI and healthy controls. (C=Ctrl, S=SI-ALI) (D) Alpha Diversity of gut microbiota in healthy controls and SI-ALI patients (Ace index and Shannon index). (E) Comparative analysis of the Microbial Dysbiosis Index (MDI) between healthy controls and SI-ALI patients. (F) Differential gut microbiota at the genus level between SI-ALI versus healthy controls. * P<0.05; ** P<0.01.