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. 2002 Sep 16;99(20):12633–12638. doi: 10.1073/pnas.192137799

Figure 3.

Figure 3

Concentration-dependent fibrillogenesis. Below the critical concentration, no fibril is formed. When the monomer concentration is higher than the critical concentration, the monomer nucleates and condenses to form the fibril. The fibrillogenesis continues until the equilibrium is achieved when the monomer concentration drops to or below the critical concentration. The length of time before fibril formation commences is called lag time.