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The effect of sugar configuration on fibrillization. The CD spectra of 0.05 mM peptides in 20 mM NaOAc buffer with 140 mM NaCl (pH 3.7) were recorded after different incubation times. Black solid line, S135-β-GlcNAc incubated for 4 weeks; red solid line, S135-β-GalNAc incubated for 4 weeks; black dashed line, S132-α-GalNAc incubated for 2 weeks only; red dashed line, 0.05 mM S132-β-GlcNAc incubated for 4 weeks.
