TABLE 3.
Summary of the standard lipid parameters
Lipid* | Length (atoms) | 2a (Å) | KA (kT/Å2) | KB (kT) |
---|---|---|---|---|
diC13:0 | 13 | 34.1 ± 0.5 | 0.576 ± 0.03 | 14 ± 2 |
diC14:0 | 14 | 35.2 ± 0.6 | 0.565 ± 0.05 | 14 ± 2 |
C18:0/1 | 18 | 40.7 ± 0.6 | 0.568 ± 0.03 | 21 ± 2 |
diC18:1c9 | 18 | 36.9 ± 0.4 | 0.638 ± 0.04 | 20 ± 2 |
diC18:2 | 18 | 34.9 ± 0.3 | 0.596 ± 0.05 | 10 ± 2 |
diC18:3 | 18 | 34.3 ± 0.6 | 0.588 ± 0.08 | 9.3 ± 1 |
diC20:4 | 20 | 34.4 ± 0.7 | 0.603 ± 0.02 | 10 ± 1 |
diC22:1 | 22 | 43.7 ± 0.5 | 0.634 ± 0.02 | 29 ± 3 |
The data is from Rawicz et al. (2000). kT for T = 300 K. Length is the number of carbon atoms that comprise each of the two tails. The full names of the lipids are: 1,2-ditridecanoyl-sn-glycero-3-phosphocholine (diC13:0); 1,2-dimyristoyl-sn-glycero-3-phosphocholine (diC14:0); 1-oleoyl-2-stearoyl-sn-glycero-3-phosphocholine (C18:0/1); 1,2-dioleoyl-sn-glycero-3-phosphocholine (diC18:1c9); 1,2-dilinoleoyl-sn-glycero-3-phosphocholine (diC18:2); 1,2-dilinoleoyl-sn-glycero-3-phosphatidylcholine (diC18:3); 1,2-diarachidonoyl-sn-glycero-3-phosphocholine (diC20:4); 1,2-dierucoyl-sn-glycero-3-phosphocholine (diC22:1). For estimates of bilayer half thickness as a function of acyl-chain length, we have fit the peak-to-peak headgroup separation to acyl-chain length for the saturated lipids above. We have used the relation: 2a = 1.3n + 16.6 Å, (136), but slightly more elaborate formulas have been discussed in Bilayer Interface Energy. When discussing the lipids used by Perozo we have used the same naming convention he employed: PC12 (12:0 dilauroyl-phosphatidylcholine), PC10 (10:0 dicaproyl-phosphatidylcholine), PC16 (16:1 dipalmitoleoyl-phosphatidylcholine), PC18 (18:1 dioleoyl-phosphatidylcholine), and PC20 (20:1 eicosenoyl-phosphatidylcholine).
Indicates the lipid numbers used for standard values in calculations.