TABLE 1.
Physical parameters used in the simulation
Parameter | Value | Reference |
---|---|---|
Virus diameter | 90 nm | Murphy et al. (1995) |
Length virus attachment protein | 8 nm | Murphy et al. (1995) |
Length cellular receptor | 6.3 nm | Kwong et al. (1998) |
Length of unstressed bond | 14.3 nm | |
Number of virus attachment proteins on virus surface | 72 | Hlavacek et al. (1999) |
Bond spring constant | 1.2 × 10−1 N/m | Chang and Hammer (2000) |
Transition-state spring constant | 1.1 × 10−1 N/m | Chang and Hammer (2000) |
Physiological cellular receptor density | 6.3 × 1011 mol/cm2 | Dimitrov et al. (1992) |
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1.4 × 105/s | Dimitrov et al. (1992) |
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3 × 10−4/s | Dimitrov et al. (1992) |
δt | 1 ns | English and Hammer (2004) |