Figure 1.

Comparison of transcriptional effects in bur6–1 and spt15–601 strains. Whole-genome expression analysis was performed by using Affymetrix YE6100 arrays on RNA prepared from strains containing bur6–1 or spt15–601 mutations. BUR6 encodes the yeast NC2 α subunit, whereas the spt15–601 TBP mutation is defective for binding NC2. (A) The number of transcripts that are detected in the spt15–601 and bur6–1 mutant strain and the number of transcripts that are affected, increase, or decrease 2-fold or greater relative to a wild-type strain are presented. The percent of transcripts that are affected, increase, or decrease relative to wild type are shown in parentheses. (B) The extent of overlap between the affected transcripts in the bur6–1 and spt15–601 strains are depicted diagrammatically, with the overlap between transcripts that increase shown on the left, and overlap between transcripts that decrease shown on the right.