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A Mie theory model based on a volume-averaged, homogeneous index of refraction is not compatible with scattering measured from cells subjected to photodynamic insult. The open squares are the angularly resolved scattering data from the treated cells. The solid line is the Mie theory fit of Eq. 6 to the control cell data, and the two dashed lines show the predictions of a model based on a homogeneous refractive index that is diluted by influx of cytosol into the mitochondrial volume.
