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. 2005 Mar 4;88(6):3770–3779. doi: 10.1529/biophysj.104.055269

TABLE 1.

Effect of the parameter d

d Unambiguous Random
0.15 17 18
0.25 4.6 4.9
0.45 2.3 2
0.75 1.3 2.8
1.15 1.1 86
d Two substitutions 8 × GT
0.25 6.3 1.1
0.35 3.2 2.8
0.45 1.6 12

(Top) Total recognition time (×106) for an unambiguous sequence and for a realistic random sequence, for different values of d. (Bottom) Ratio of the total recognition time for a sequence with two substitutions (respectively, a sequence with eight dinucleotide repeats) to the total recognition time for an unambiguous sequence, for different values of d. One-hundred simulations per value, N = 20, Ehom = −5.5, Ehet = −1.5, Erep = 2, and Ecoopbind = 2.