TABLE 1.
Dissociation rates and xβ values of A1 bonds with wild-type and mutated GP Ib-IX receptors
| Cell type |
 (s−1) |
xβ (nm) |
|---|---|---|
| Wild-type | 5.47 ± 0.25 | 0.71 ± 0.03 |
| 231 mutant | 7.99 ± 0.53 | 0.97 ± 0.06 |
| 232 mutant | 10.8 ± 0.34 | 1.4 ± 0.04 |
| 233 mutant | 4.07 ± 0.31 | 0.47 ± 0.03 |
| 235 mutant | 3.73 ± 0.29 | 0.44 ± 0.03 |
| 237 mutant | 3.27 ± 0.22 | 0.45 ± 0.03 |
| 239 mutant | 4.21 ± 0.38 | 0.55 ± 0.05 |
| Wild-type (Doggett, 2002) | 3.45 ± 0.37 | 0.016 ± 0.002 |
| Wild-type (Kumar, 2003) | 5.66 | 0.0058 |
| Wild-type (Miura, 2000) | 0.0038 | — |
| 233 (Doggett, 2003) | 0.67 ± 0.11 | 0.031 ± 0.005 |
| 237 (Kumar, 2003) | 2.56 | 0.0089 |
For each cell type in our experiments, there were 170 A1/GP Ib-IX adhesive events and statistically significant differences among the 
values (p < 0.05).