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. 2005 Mar 18;88(6):4421–4433. doi: 10.1529/biophysj.104.057745

FIGURE 6.

FIGURE 6

Model-generated fits of Ca2+ uncaging from DMn with Mg2+ present. Examples of data obtained when uncaging Ca2+ in the presence of Mg2+ (○). Left panel, [Mg2+]T/[DMn]T = 0.2; right panel, [Mg2+]T/[DMn]T = 1.2. For comparison, the top traces in each data set represent Ca2+ uncaging in the absence of Mg2+ with a comparable ΔF/F value (•; fitted curves have been omitted for clarity). (a) Fits using model (a). (b) Fits using model (b). Insets show on a faster timescale the largest curves with Mg2+ present. It is clear that model (b) is far better than model (a) in fitting the fast initial rise and fall in fluorescence.