Figure 2.
XPC and p53 expression in WI38 and WI38-E6 cells. (A) Expression of XPC and p53 was evaluated in WI38 normal human fibroblasts as well as in the E6-transformed p53 null counterpart. The times indicated are incubation times after treatment with 15 J/m2 UV irradiation. Antibodies used are as described above. unirr, unirradiated. (B) UV dose response of p53 and XPC expression was studied by using WI38 and WI38-E6 cells. Cells were harvested 48 h after UV treatment. Fold inductions were calculated as described in the Fig. 1 legend.