Table 1.

Plasma and urine chemistries in Zmpste24^−/− mice

	Zmpste24+/+	Zmpste24−/−
Glucose, mg/dl	191  ± 61	176  ± 77
Total protein, g/dl	6.7  ± 1.0	5.8  ± 2.8
Alanine aminotransferase, units/liter	61  ± 37	44  ± 32
Aspartate aminotransferase, units/liter	141  ± 71	120  ± 83
Alkaline phosphatase, units/liter	83  ± 9	59  ± 9*
Calcium, mmol/liter	9.22  ± 0.67	9.64  ± 0.70
Phosphate, mmol/liter	7.84  ± 4.47	9.78  ± 4.02
Urinary deoxypyridinoline, nmol/mg creatinine (14-week-old mice)	0.22  ± 0.04	0.25  ± 0.03
Urinary deoxypyridinoline, nmol/mg creatinine (4-week-old mice)	0.21  ± 0.03	0.21  ± 0.04

Data are presented as mean and SD; n = 6–10 adult mice per group, ages 15–24 weeks except as indicated. 

^*, P < 0.01. Except for alkaline phosphatase, no differences were significant (P > 0.05).