Fig. 4.

Cd²⁺ (0.2 mM) suppressed time dependence of I_Cl,swell at positive potentials and revealed a delayed rectifier current. Examples from two myocytes are shown. A, B, C: data from one myocyte. D, E, F: data from a second myocyte. Families of currents after swelling in 0.7T solution (A and D), after exposure to Cd²⁺ (B and E), and Cd²⁺ -sensitive current (C and F) are shown. Cd²⁺ inhibited the time dependence of I_Cl,swell at positive potentials and had a variable effect on the steady-state current. After Cd²⁺ block, a slowly activating outward component of current was apparent. Block of I_Cl,swell was greatest in the second myocyte (D-F).