Fig. 6.

Cd²⁺ plus Ba²⁺ eliminated the time dependence of I_Cl,swell at strongly positive potentials. To test whether Cd²⁺ (0.2 mM) and Ba²⁺ (1 mM) shifted the onset of I_Cl,swell inactivation to more positive voltages, the membrane voltage was stepped from −60 mV to potentials between −60 and +100 mV. A: I-V relationships in 1T solution and after 10 min of swelling in 0.7T solution. B and C: families of currents in 1T and 0.7T solutions, respectively. D: swelling-induced difference current. I_Cl,swell remained time independent to at least +100 mV.