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[Preprint]. 2026 Apr 1:2026.03.30.26349798. [Version 1] doi: 10.64898/2026.03.30.26349798

Table 1:

Participant demographics

Survey Adolescent (N=41) Adult (N=151) Caregiver (N=49)
Sex
Female 27 (65.9%) 92 (60.9%) 44 (89.8%)
Male 14 (34.1%) 59 (39.1%) 5 (10.2%)
Previous TB diagnosis
Yes 1 (2.4%) 28 (18.5%) 3 (6.1%)
No 40 (97.6%) 123 (81.5%) 46 (93.9%)
Highest education completed
No formal education 0 (0%) 25 (16.6%) 7 (14.3%)
Primary education 16 (39.0%) 62 (41.1%) 23 (46.9%)
Secondary or higher education 25 (61.0%) 61 (40.4%) 19 (38.8%)
Willing to receive a TB vaccine
Yes 36 (87.8%) 112 (74.2%) 36 (73.5%)
Maybe 5 (12.2%) 24 (15.9%) 9 (18.4%)
No 0 (0%) 15 (9.9%) 4 (8.2%)
Interview Adolescent (N=6) Adult (N=11) Caregiver (N=6)
Willing to receive a TB vaccine (from survey)
Yes 6 (100%) 9 (81.8%) 4 (66.7%)
Maybe 0 (0%) 2 (18.2%) 1 (16.7%)
No 0 (0%) 0 (0%) 1 (16.7%)
Sex
Female 2 (33.3%) 0 (0%) 6 (100%)
Male 4 (66.7%) 11 (100%) 0 (0%)
Previous TB diagnosis
Yes 0 (0%) 6 (54.5%) 0 (0%)
No 6 (100%) 5 (45.5%) 6 (100%)
Highest education completed
No formal education 0 (0%) 0 (0%) 0 (0%)
Primary education 3 (50%) 6 (54.5%) 3 (50%)
Secondary or higher education 3 (50%) 5 (45.5%) 3 (50%)

In a multivariable logistic model including demographic factors, previous vaccination experiences, and knowledge/experience of TB, we found that the strongest determinant of willingness to vaccinate was age: adolescents were nearly six times more willing to receive a new TB vaccine as adults (adjusted OR: 5.6, 95% CI: 1.9–19.6). Participants who reported previous issues accessing vaccines were more than three times as willing to receive a new TB vaccine than those who did not report previous access issues (adjusted OR: 3.3, 95% CI: 1.3–8.9). Although not significant at p = 0.05, we also found that participants reporting personal experience with TB (a friend or family member with the disease) (adjusted OR: 2.4, 95% CI: 0.8–7.9) and with a higher knowledge of TB (adjusted OR 2.6, 95% CI: 0.9–7.5) were more willing to receive a new TB vaccine. There were no missing responses for the variables used in the model. (Table 2)