Table 2.
Associations between adult/adolescent characteristics and willingness to receive a novel TB vaccine in southern Mozambique, 2023–2024
| Variable | N (%) | % willing to be vaccinated | Unadjusted OR (95% CI)1 | p-value | Adjusted OR (95% CI)1 | p-value |
|---|---|---|---|---|---|---|
| Demographic variables | ||||||
| Highest education completed | ||||||
| None | 25 (13.0%) | 80.0% | 1.0 (ref) | - | 1.0 (ref) | - |
| Primary | 78 (40.6%) | 83.3% | 1.3 (0.4, 3.9) | 0.7 | 2.8 (0.7, 11.1) | 0.15 |
| Secondary or higher | 89 (46.4%) | 70.8% | 0.6 (0.2, 1.8) | 0.36 | 1.0 (0.3, 3.9) | 0.96 |
| Sex | ||||||
| Female | 119 (62.0%) | 78.2% | 1.0 (ref) | - | 1.0 (ref) | - |
| Male | 73 (38.0%) | 75.3% | 0.9 (0.4, 1.7) | 0.65 | 0.5 (0.2, 1.4) | 0.19 |
| Religion | ||||||
| Christian2 | 121 (63.0%) | 74.4% | 1.0 (ref) | - | 1.0 (ref) | - |
| Other3 | 71 (37.0%) | 81.7% | 1.5 (0.7, 3.2) | 0.25 | 1.5 (0.6, 3.6) | 0.37 |
| Age group | ||||||
| Adult | 151 (78.6%) | 74.2% | 1.0 (ref) | - | 1.0 (ref) | |
| Adolescent | 41 (21.4%) | 87.8% | 2.5 (0.9, 6.8) | 0.073 | 5.6 (1.9, 19.6) | 0.0037 |
| Vaccination experiences | ||||||
| Previous negative vaccination experience | ||||||
| No | 133 (69.3%) | 79.7% | 1.0 (ref) | - | 1.0 (ref) | - |
| Yes | 59 (30.7%) | 71.2% | 0.6 (0.3, 1.3) | 0.20 | 0.8 (0.3, 1.9) | 0.6 |
| Previous issues accessing vaccines | ||||||
| No | 122 (63.5%) | 72.1% | 1.0 (ref) | - | 1.0 (ref) | - |
| Yes | 70 (36.5%) | 85.7% | 2.3 (1.1, 5.0) | 0.034 | 3.3 (1.3, 8.9) | 0.014 |
| TB knowledge and experience | ||||||
| Personal TB experience (friend / family member with TB) | ||||||
| No | 103 (53.6%) | 73.8% | 1.0 (ref) | - | 1.0 (ref) | - |
| Yes | 89 (46.4%) | 80.9% | 1.5 (0.8, 3.0) | 0.24 | 2.4 (0.8, 7.9) | 0.12 |
| TB knowledge level | ||||||
| Low | 37 (19.3%) | 62.2% | 1.0 (ref) | - | 1.0 (ref) | - |
| Moderate | 32 (16.7%) | 78.1% | 2.2 (0.7, 6.3) | 0.15 | 1.3 (0.4, 4.7) | 0.67 |
| High | 123 (64.1%) | 81.3% | 2.6 (1.2, 5.9) | 0.018 | 2.6 (0.9, 7.5) | 0.073 |
| Perceived risk of TB | ||||||
| Low | 93 (48.4%) | 74.2% | 1.0 (ref) | - | 1.0 (ref) | - |
| Moderate | 65 (33.9%) | 86.2% | 2.2 (0.9, 5.0) | 0.072 | 2.1 (0.8, 5.7) | 0.14 |
| High | 34 (17.7%) | 67.6% | 0.7 (0.3, 1.7) | 0.47 | 0.6 (0.1, 2.2) | 0.41 |
1
OR=Odds Ratio, CI=Confidence Interval
2
Catholic, Evangelical, Indeterminate Christian
3
Zionism, Atheism, Islamic, Other